Faculty Initiatives > Imaging

Imaging

"The overall aim of my laboratory is to understand the parameters that define the health of preimplantation embryos and embryonic stem cells by using genetic, immunological, and imaging methods.  The preimplantation period of development starts at the moment of fertilization and continues until implantation of the embryo into the uterine wall, a process that takes 5 days in the mouse and 6 days in humans.  During the preimplantation period the embryos are free floating in the reproductive tract. This makes it possible to remove the embryos from their mothers and subject them to well-controlled experimental protocols.  We use the mouse as a model system with the long-range goal of using results from our experiments on mice to develop methods to identify healthy human embryos created in in vitro fertilization (IVF) clinics. "

Prof. Carol M. Warner

 
Faculty Research in the News Professor Carol Warner

ANTIBIOTIC BOOST: Matthews Distinguished Professor Carol Warner’s research on In-Vitro Fertilization and single embryo fertilization was featured in a front-page story in the August 24th issue of The Boston Globe’s Science section.).
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Imaging publications by professor warner in 2004:

Warner, C.M., Newmark, J.A., Comiskey, M., De Fazio, S.R., O'Malley, D.M., Rajadhyaksha, M., Townsend, D.J., McKnight, S., Roysam, B., Dwyer, P.J., and DiMarzio, C.A. (2004) Genetics and imaging to asses oocyte and preimplantation embryo health. Reprod., Fertil., Develop., in press.

Comiskey, M., Warner, C.M., and Schust, D.J. (2004) MHC molecules of the preimplantation embryo and trophoplast. In: G. Mor (ed.) Immunology of Pregnancy, Landes Bioscience, Georgetown, TX, in press.

Assounga, A.G. and Warner, C.M. (2004) Memory T lymphocytes of young and old C57BL/6 mice express high levels of class I major histocompatibility complex protein. Growth, Develop., Aging, in press.

Assounga, A.G. and Warner, C.M. (2004) Transcription of MHC class I and peptide transporters (Tap1 and Tap2) genes is up-regulated with age. Immunology, in press.

Warner, C.M., Comiskey, M., Clisham, P.R., and Brenner, C.A. (2004) Soluble HLA-G (sHLA-G)—A predictor of IVF outcome?  J. Asst. Reprod. Gen., in press.

 
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